Title of article
Fiber-derived butyrate and the prevention of colon cancer
Author/Authors
Christian A. Hassig، نويسنده , , Jeffrey K. Tong، نويسنده , , Stuart L. Schreiber، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 1997
Pages
7
From page
783
To page
789
Abstract
Inhibition of the enzyme histone deacetylase by butyrate results in the direct transcriptional upregulation of the cyclin-dependent kinase inhibitor p21/Cip1/WAF1. We discuss a small-molecule-mediated signaling pathway to explain the suspected anti-colon-cancer properties of fiber-derived butyrate.
Journal title
Chemistry and Biology
Serial Year
1997
Journal title
Chemistry and Biology
Record number
1157968
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