Title of article
Organelle pH studies using targeted avidin and fluorescein–biotin Original Research Article
Author/Authors
Minnie M Wu، نويسنده , , Juan Llopis، نويسنده , , Stephen Adams، نويسنده , , J. Michael McCaffery، نويسنده , , Markku S. Kulomaa، نويسنده , , Terry E. Machen، نويسنده , , Hsiao-Ping H Moore، نويسنده , , Roger Y. Tsien، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 2000
Pages
13
From page
197
To page
209
Abstract
Abstract
Background: Mammalian organelles of the secretory pathway are of differing pH. The pH values form a decreasing gradient: the endoplasmic reticulum (ER) is nearly neutral, the Golgi is mildly acidic and the secretory granules are more acidic still (∼pH 5). The mechanisms that regulate pH in these organelles are still unknown.
Keywords
* H+ leak , * Targeted fluorescence , * H+ pump , * Flubi-2
Journal title
Chemistry and Biology
Serial Year
2000
Journal title
Chemistry and Biology
Record number
1158239
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