• Title of article

    A Molecular Warhead and Its Target: Tissue Transglutaminase and Celiac Sprue Review Article

  • Author/Authors

    Detlef Schuppan، نويسنده , , Walburga Dieterich، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    199
  • To page
    201
  • Abstract
    The substitution of a glutamine residue with 6-diazo-5-oxo-norleucine (DON) transforms an immunodominant gluten peptide into a potent inhibitor of tissue transglutaminase. DON-modified peptides could be useful for the study and therapy of celiac sprue.
  • Journal title
    Chemistry and Biology
  • Serial Year
    2003
  • Journal title
    Chemistry and Biology
  • Record number

    1158617