• Title of article

    HAT Trick: p300, Small Molecule, Inhibitor

  • Author/Authors

    Melanie Ott، نويسنده , , Eric Verdin، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    417
  • To page
    418
  • Abstract
    p300 is an acetyltransferase that targets histone and nonhistone proteins for lysine acetylation. Based on a p300 structure, have conducted an in silico screen for active site small molecule inhibitors of p300. We describe this important discovery and its potential therapeutic applications.
  • Journal title
    Chemistry and Biology
  • Serial Year
    2010
  • Journal title
    Chemistry and Biology
  • Record number

    1159856

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1159856