Bacteriophage as a Novel Antibacterial Agent in Industry and Medicine

Bacteriophages are viruses that infect bacteria, and are distinct from animal and plant viruses that could have either lytic or lysogenic cycle. Lytic phages known as candidates for phage therapy, since they rapidly replicate into their host and lyse them. Theoretically, phages have more than a few benefits over routine antibiotics. They are extremely specific for their targeted hosts and also are safe for human, because they have no activity against eukaryotic cells. Over this time, phages were used to treat various infections. Although, phages have a number of advantages over antibiotics, their industrial production as a commercial product ceased in most of the western European countries after the introduction of antibiotics. These days, by increasing of antibiotics resistance and inefficiency of antibiotics against bacterial biofilms, there is renewed global interest in phage applications as potentially powerful antibacterial agents. Different published paper through the world indicates bacteriophages could be recruited as suitable agent for therapeutic purposes in medicine and food industry. Therefore, here we tried to review most of these ideas about phage application as a rapid review.