Estimation for the heating effect of magnetic nanoparticles in perfused tissues

This work uses the transient bio-heat equation to predict the temperature rise behavior occurring in biological tissues during magnetic nanoparticles hyperthermia. A numerical scheme is proposed to solve the bio-heat transfer problem in a bi-layered spherical tissue with blood perfusion and metabolism. The analytical solution evidences the accuracy of the numerical scheme and examines the results in the literature.