• Title of article

    Reversible modification of tissue-type plasminogen activator by methylphosphonate esters Original Research Article

  • Author/Authors

    In spite of their rapid aqueous hydrolysis، نويسنده , , 4-nitrophenyl 4-X-phenacyl methylphosphonates (X = H، نويسنده , , (PMN) CH3، نويسنده , , CH3O، نويسنده , , Cl and NO2) inactivate many serine proteases of the pancreatic and blood coagulation systems efficiently. The rate constants، نويسنده , , ki/Ki for the ، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    7
  • From page
    523
  • To page
    529
  • Abstract
    Qinjian Zhao, Ildiko M Kovach
  • Keywords
    Fibrinolytic enzymes , serine protease inhibition , serine protease , t-PA inhibition , serine hydrolase inhibition
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    1996
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1300714