Title of article
Use of BOP-Cl in the presence of Boc-amino monothioacids for the thioacylation of iminoacid residues Original Research Article
Author/Authors
Hoang-Thanh Le، نويسنده , , Jean-François Gallard، نويسنده , , Michel Mayer، نويسنده , , Béatrice Felenbok and Eric Guittet، نويسنده , , Robert Michelot، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
9
From page
2201
To page
2209
Abstract
BOP-Cl was found to be an efficient coupling reagent for the introduction of thiopeptide bonds on imino acid residues (Pro, Sar). Boc-amino monothioacids were coupled at moderate temperature (0 °C-RT) with fair yields and with retained optical purity. The mechanism of the coupling reaction is discussed.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1996
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301007
Link To Document