Title of article
Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase Original Research Article
Author/Authors
Dale L. Boger، نويسنده , , Marc A. Labroli، نويسنده , , Thomas H. Marsilje، نويسنده , , Qing Jin، نويسنده , , Michael P. Hedrick، نويسنده , , Stephen J. Baker، نويسنده , , Jae Hoon Shim، نويسنده , , Stephen J. Benkovic، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
12
From page
1075
To page
1086
Abstract
The synthesis and evaluation of a series of conformationally restricted analogues of 10-formyl-tetrahydrofolate as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) or aminoimidazole carboxamide transformylase (AICAR Tfase) are reported.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2000
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301012
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