Title of article
Biotransformation of a 4(20),11(12)-taxadiene derivative Original Research Article
Author/Authors
Di-Hua Sun، نويسنده , , Françoise Sauriol، نويسنده , , Orval Mamer، نويسنده , , Lolita O. Zamir، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
8
From page
793
To page
800
Abstract
A 4(20),11(12)-taxadiene derivative was converted to hydroxylated derivatives by Cunninghamella elegans AS3.2033 and Cunninghamella elegans var chibaensis ATCC 20230. Both microorganisms led to C-1 hydroxylations and conversion to a C-15-hydroxylated abeo-taxane. Additional products from the two fungi differed: a C-14 oxidation and a trans–cis isomerization of the cinnamoyl for one and an unprecedented hydroxylation at C-17 for the other.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2001
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301445
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