Title of article
Endothelin receptor antagonists: synthesis and structure–activity relationships of substituted benzothiazine-1,1-dioxides Original Research Article
Author/Authors
K.A. Berryman، نويسنده , , J.J. Edmunds، نويسنده , , A.M. Bunker، نويسنده , , S. Haleen، نويسنده , , J. Bryant، نويسنده , , K.M. Welch، نويسنده , , A.M. Doherty، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
10
From page
1447
To page
1456
Abstract
The development of benzothiazine-1,1-dioxide derivatives as a new structural class of potent endothelin receptor antagonists is described. Structure–activity relationships (SAR) revealed that PD164800 (1) is a potent antagonist of the ETA receptor subtype.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1998
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301665
Link To Document