Title of article
Synthesis and structure–activity relationship of diarylamide urea derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells Original Research Article
Author/Authors
Haruhisa Ogita، نويسنده , , Yoshiaki Isobe، نويسنده , , Haruo Takaku، نويسنده , , Rena Sekine، نويسنده , , Yuso Goto، نويسنده , , Satoru Misawa، نويسنده , , Hideya Hayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
7
From page
1865
To page
1871
Abstract
A series of diarylamide urea derivatives were synthesized and evaluated for their inhibitory activities against human coronary artery smooth muscle cells (SMCs) and human coronary artery endothelial cells (ECs). Compound 2o was superior to the lead compound, Tranilast, in terms of its potency of the inhibitory activity and cell selectivity.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2002
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302115
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