Title of article
Membrane-Permeant derivatives of mannose-1-phosphate Original Research Article
Author/Authors
Synke Rutschow، نويسنده , , Joachim Thiem، نويسنده , , Christian Kranz، نويسنده , , Thorsten Marquardt، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
7
From page
4043
To page
4049
Abstract
For treatment of congenital disorder of glycosylation type Ia (CDG-Ia) membrane-permeant derivatives of mannose-1-phosphate are required. Employing biologically cleavable phosphate protecting groups advantageous precursor derivatives could be synthesized following a facile approach. Their enzymatic cleavages using esterase from porcine liver (E.C. 3.1.1.1) were investigated.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2002
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302478
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