Title of article
QSAR study of quinolinediones with inhibitory activity of endothelium-Dependent vasorelaxation by CoMSIA Original Research Article
Author/Authors
Hea-Young Park Choo، نويسنده , , Suyoung Choi، نويسنده , , Chung-Kyu Ryu، نويسنده , , Hwa-Jung Kim، نويسنده , , In Young Lee، نويسنده , , Ae Nim Paeb، نويسنده , , Hun Yeong Koh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
2019
To page
2023
Abstract
The 3D-QSAR study of quinolinediones which showed potent inhibitory effect on the acetylcholine induced vasorelaxation of rat aorta with the endothelium was conducted by CoMSIA. The statistical result, cross-validated q2 (0.741) and r2 (0.960) values, gave reliability to the prediction of inhibitory activity of this series.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2003
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302687
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