• Title of article

    Synthesis and biological evaluation of novel turn-modified gramicidin S analogues Original Research Article

  • Author/Authors

    Gijsbert M. Grotenbreg، نويسنده , , Emile Spalburg، نويسنده , , Albert J de Neeling، نويسنده , , Gijsbert A. van der Marel، نويسنده , , Herman S. Overkleeft، نويسنده , , Jacques H. van Boom، نويسنده , , Mark Overhand، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    7
  • From page
    2835
  • To page
    2841
  • Abstract
    The synthesis of novel gramicidin S analogues having additional functionalities in the turn region by employing a biomimetic approach is described. The preservation of β-sheet character in all analogues was established by NMR and the biological activity was evaluated.
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2003
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1302767