Title of article
Synthesis and cytotoxic activity of some new azapyranoxanthenone aminoderivatives Original Research Article
Author/Authors
George Kolokythas، نويسنده , , Ioannis K. Kostakis، نويسنده , , Nicole Pouli، نويسنده , , Panagiotis Marakos، نويسنده , , Dimitris Kletsas، نويسنده , , Harris Pratsinis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
8
From page
4591
To page
4598
Abstract
A series of novel azapyranoxanthenones, bearing structural similarity to the acridone alkaloid acronycine have been designed and synthesized. Their in vitro cytotoxicities against the murine L1210 leukemia and the human solid tumor HT-29 cell lines have been investigated. The new derivatives exhibited interesting cytotoxic activity and were more potent than the parent compound.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2003
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302779
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