• Title of article

    Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid Original Research Article

  • Author/Authors

    Tatiana Fonseca، نويسنده , , Barbara Gigante، نويسنده , , M.Matilde Marques، نويسنده , , Thomas L. Gilchrist، نويسنده , , Erik De Clercq، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    10
  • From page
    103
  • To page
    112
  • Abstract
    Several heterocycles, such as benzimidazoles, quinoxalines and indoles incorporated into a hydrophenanthrene and naphthalene skeleton, were synthesised from two useful ortho-bromonitro precursors derived from dehydroabietic acid: methyl 12-bromo-13-nitro-deisopropyldehydroabietate and methyl 12-bromo-13,14-dinitro-deisopropyldehydroabietate. The new heterocycles were evaluated for their activity in vitro against several RNA and DNA viruses.
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2004
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1302845