Title of article
A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities Original Research Article
Author/Authors
Li Yang، نويسنده , , Lin-Hua Qin، نويسنده , , S.W. Annie Bligh، نويسنده , , A. Bashall، نويسنده , , Chao-Feng Zhang، نويسنده , , Mian Zhang، نويسنده , , Zhengtao Wang، نويسنده , , Luo-Shan Xu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
3496
To page
3501
Abstract
Investigation of phenolic patterns from the stems of Dendrobium chrysanthum by HPLC–PDA–MS has led to the isolation of a new phenanthrene derivative with a spirolactone ring, dendrochrysanene (1), that proved to suppress the mRNA level of TNF-α, IL8, IL10, and iNOS in murine peritoneal macrophages. The structure of 1 was characterized on the basis of various NMR (1H, 13C, 1H–1H COSY, HMQC, and HMBC), mass spectrometry, and X-ray crystal diffraction data.
Keywords
Anti-inflammatory , spirolactone , Dendrochrysanene , Chrysotoxin , Dendrobium chrysanthum , Moscatin , Phenanthrene
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303415
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