Title of article
Efficient one-pot synthesis of biologically active polysubstituted aromatic amines Original Research Article
Author/Authors
Dirk Menche، نويسنده , , Fatih Arikan، نويسنده , , Jun Li، نويسنده , , Sven Rudolph، نويسنده , , Florenz Sasse، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
7311
To page
7317
Abstract
An efficient and modular one-pot synthesis of polysubstituted aromatic amines by a mild reductive amination procedure is described and the biological potential of these nitrogen-centered compounds is demonstrated by growth inhibition of murine connective tissue cells and microscopy-based morphological studies.
Keywords
Aromatic amines , Diversity-oriented synthesis , One-pot synthesis , Cytotoxicity , Reductive amination
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2007
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303818
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