Title of article
Inhibitory property of the Piper betel phenolics against photosensitization-induced biological damages Original Research Article
Author/Authors
Soumyaditya Mula، نويسنده , , Debashish Banerjee، نويسنده , , Birija S. Patro، نويسنده , , Sayanti Bhattacharya، نويسنده , , Atanu Barik، نويسنده , , Sandip K. Bandyopadhyay، نويسنده , , Subrata Chattopadhyay، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
7
From page
2932
To page
2938
Abstract
The Piper betel phenolics, allylpyrocatechol (APC) and chavibetol (CHV), were found to protect photosensitization-mediated lipid peroxidation (LPO) of rat liver mitochondria effectively, APC being significantly more potent. The better activity of APC vis-à-vis CHV could be attributed to its higher reactivity with 1O2, as revealed from the rate constant values of 1O2 quenching by the respective phenolics. APC also prevented the detrimental effects of the Type II photosensitization-induced toxicity to mouse fibroblast L929 cells. The results suggest that APC may play an important role in protecting biological systems against damage, by eliminating 1O2 generated from certain endogenous photosensitizers.
Keywords
Cells , Photosensitization , Lipids , Protection
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304126
Link To Document