Title of article
Novel A-ring homodimeric C-3-carbamate analogues of 1α,25-dihydroxyvitamin D3: Synthesis and preliminary biological evaluation Original Research Article
Author/Authors
Daniel Oves، نويسنده , , Susana Fern?ndez، نويسنده , , Lieve Verlinden، نويسنده , , Roger Bouillon، نويسنده , , Annemieke Verstuyf، نويسنده , , Miguel Ferrero، نويسنده , , Vicente Gotor، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
8
From page
7512
To page
7519
Abstract
The synthesis of a new class of vitamin D3 analogues in which two units of 1α,25-dihydroxyvitamin D3 are linked at the C-3 position by a dicarbamate functionality of variable length is described. The analogues demonstrated no affinity for the vitamin D receptor and possessed no antiproliferative or transactivating properties.
Keywords
Vitamin D3 analogues , Enzymatic catalysis , Biological evaluation
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305237
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