Title of article
Synthesis of penaresidin derivatives and its biological activity Original Research Article
Author/Authors
Kengo Ohshita، نويسنده , , Haruaki Ishiyama، نويسنده , , Yohei Takahashi، نويسنده , , Junji Ito، نويسنده , , Yuzuru Mikami، نويسنده , , Jun’ichi Kobayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
4910
To page
4916
Abstract
A series of stereoisomers for the azetidine ring of penaresidin B was synthesized and their cytotoxic and antimicrobial activities were evaluated. Among six synthetic isomers 1–6, isomers 4 and 5 showed relatively potent cytotoxic activity against A549 (lung) and HT29 (colon) tumor cells as well as antibacterial activity.
Keywords
Penaresidin derivatives , Azetidine ring , Cytotoxicity , Antimicrobial activity
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2007
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305900
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