Title of article
Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles Original Research Article
Author/Authors
Damien Cressier، نويسنده , , Caroline Prouillac، نويسنده , , Pierre Hernandez، نويسنده , , Christine Amourette، نويسنده , , Michel Diserbo، نويسنده , , Claude Lion، نويسنده , , Ghassoub Rima، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
10
From page
5275
To page
5284
Abstract
In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.
Keywords
Radioprotection , Phosphorothioates , Thiosulfonic acid , Benzothiazole , Thiadiazole , antioxidant
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2009
Journal title
Bioorganic and Medicinal Chemistry
Record number
1306189
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