Title of article
Nakijiquinones G–I, new sesquiterpenoid quinones from marine sponge Original Research Article
Author/Authors
Yohei Takahashi، نويسنده , , Takaaki Kubota، نويسنده , , Junji Ito، نويسنده , , Yuzuru Mikami، نويسنده , , Jane Fromont، نويسنده , , Jun’ichi Kobayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
7561
To page
7564
Abstract
Three new sesquiterpenoid quinones, nakijiquinones G–I (1–3), containing a different amino group derived from amino acids have been isolated from Okinawan marine sponges of the family Spongiidae, and the structures and relative stereochemistry of 1–3 were elucidated on the basis of the spectral data. Nakijiquinones G–I (1–3) showed modest cytotoxicity and inhibitory activity against HER2 kinase, while nakijiquinone H (2) exhibited antimicrobial activity.
Keywords
Marine sponge , Sesquiterpenoid quinones , Nakijiquinones G–I
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1306808
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