Title of article
3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication Original Research Article
Author/Authors
Daniela Iannazzo، نويسنده , , Anna Piperno، نويسنده , , Giovanni Romeo، نويسنده , , Roberto Romeo، نويسنده , , Ugo Chiacchio، نويسنده , , Antonio Rescifina، نويسنده , , Emanuela Balestrieri، نويسنده , , Beatrice Macchi، نويسنده , , Antonio Mastino، نويسنده , , Riccardo Cortese، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
6
From page
9610
To page
9615
Abstract
A new class of compounds able to block the replication of subgenomic HCV RNA in liver cells is described. 3-Amino-2(5H)furanones 4 may be regarded as diketoacid analogues and were obtained by basic rearrangement of the isoxazolidine nucleus.
Keywords
DKA , 1 , 3-dipolar cycloaddition , isoxazolidines , HCV , furanones
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1306989
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