Nanocomposites of poly(l-lactide) and surface modified magnesia nanoparticles: Fabrication, mechanical property and biodegradability Original Research Article

A novel nanocomposite based on biodegradable poly(l-lactide) (PLLA) was prepared by the incorporation of surface modified magnesia (g-MgO) nanoparticles using a solution casting method. The mechanical properties, biodegradable properties and protein adhesion behavior of the g-MgO/PLLA nanocomposites were investigated. Scanning electron microscopy (SEM) results showed that g-MgO nanoparticles could comparatively uniformly disperse in PLLA matrix. The addition of g-MgO nanoparticles to PLLA matrix improved the tensile strength and elastic modulus, whereas reduced the elongation at break. The mass loss results showed that the nanocomposites with higher g-MgO content had faster degradation rates. The in vitro pH value determination results indicated that the g-MgO nanoparticles could neutralize effectively the lactic acid resulting from the degradation of PLLA. The g-MgO/PLLA nanocomposites exhibited enhanced protein adsorption, i.e., with the increase of g-MgO content, the amount of protein adsorption increased. The (5 wt%)g-MgO/PLLA nanocomposites adsorbed 33% more protein than the pure PLLA.