Title of article
Ruthenium complexes with purine derivatives: Syntheses, structural characterization and preliminary studies with plasmidic DNA
Author/Authors
A. Garc?a-Raso، نويسنده , , J.J. Fiol، نويسنده , , A. Tasada، نويسنده , , M.J. Prieto، نويسنده , , V. Moreno، نويسنده , , I. Mata، نويسنده , , E. Molins، نويسنده , , T. Buni?، نويسنده , , A. Golobi?، نويسنده , , I. Turel، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
5
From page
800
To page
804
Abstract
Two new chloride-dimethylsulfoxide-ruthenium(III) complexes, [RuIIICl4(DMSO)(H-Hypoxanthine)] (1) and [RuIIICl4(DMSO)[H-(N6-butyladenine)]] (2), have been prepared and structurally characterized by X-ray diffraction crystallography. The Ru(III)–hypoxanthine complex 1 is the first complex where monodentate coordination of hypoxanthine through nitrogen N(3) has been observed.
Preliminary electrophoretic mobility and atomic force microscopy (AFM) studies show that both compounds interact with plasmidic DNA but the nature of the nucleobase seems to be important.
Keywords
DNA–metal complex interaction , Ruthenium , Bioinorganic chemistry , Purine derivatives , X-ray diffraction
Journal title
Inorganic Chemistry Communications
Serial Year
2005
Journal title
Inorganic Chemistry Communications
Record number
1316811
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