Chloro and acetato complexes of platinum(II) with functionalized thioethers

The chloro complexes [PtCl2(RSR′)2] (1–10) (RSR′ = MeSCH2C(O)OMe, 1; MeSCH2C(O)OEt, 2; MeSCH2C(O)Omenthyl(−), 3; MeSCH2CH2C(O)OMe, 4; , 5; EtSCH2C(O)Me, 6; MeSCH(Me)C(O)Me, 7; MeSPh, 8; MeS-o -C6H4Me, 9; and MeS-o -C6H4Et, 10) are obtained in high yield (63–90%) by reaction of [PtCl2(PhCN)2] with the proper thioether in 1/2 molar ratio, in anhydrous chloroform, at reflux under argon for ca. 10 h. The X-ray crystal structure of [PtCl2(MeS-o -C6H4Me)2] (9) shows an almost regular trans square planar geometry (triclinic, space group View the MathML sourceP1¯, a 6.806(1), b 7.789(2), c 10.085(3) Å, α 101.80(2)°, β 69.55(2)°, γ 115.27(2)°, R (F o) 0.023, View the MathML sourceRw(Fo2)0.065). The dichloro complexes react with silver acetate in a complex manner, which depends on the nature of the thioether, and only with RSR′ = MeSPh the simple diacetato complex [Pt(OAc)2(RSR′)2] is obtained as the major product.