Rhenium and technetium complexes with anionic or neutral scorpionates: An overview of their relevance in biomedical applications Review Article

This article reviews the chemistry of Re and Tc complexes anchored by anionic and neutral scorpionates with potential relevance in the field of biomedical applications, particularly in radiopharmaceutical research. For poly(azolyl)borates, the revised work focuses mainly on poly(mercaptoimidazolyl)borate tricarbonyl M(I) complexes, while for tris(pyrazolyl)methanes the revision includes M(VII) trioxo- and M(I) tricarbonyl complexes. A comprehensive update of structural, chemical, radiochemical and biological aspects relevant for the use of these compounds in the design of radiopharmaceuticals is presented and discussed.