Title of article
Reconstructing the Disease Model and Epigenetic Networks for MLL-AF4 Leukemia
Author/Authors
Zeisig، نويسنده , , Bernd B. and Cheung، نويسنده , , Ngai and Yeung، نويسنده , , Jenny and So، نويسنده , , Chi Wai Eric، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
345
To page
347
Abstract
The lack of a proper animal model has impeded understanding of the molecular mechanism of leukemia associated with the MLL-AF4 fusion. In this issue of Cancer Cell, Krivtsov et al. report a much-improved murine Mll-AF4 model and propose a molecular link with H3K79 methylation mediated by the histone methyltransferase DOT1L.
Journal title
Cancer Cell
Serial Year
2008
Journal title
Cancer Cell
Record number
1336878
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