• Title of article

    A Tumor Suppressor SIRTainty

  • Author/Authors

    Paul T. Schumacker، نويسنده , , Paul T.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    5
  • To page
    6
  • Abstract
    Sirtuin deacetylases are linked to longevity, aging, and stress responses. In this issue of Cancer Cell, Kim et al. show that SIRT3 functions as a tumor suppressor by enhancing the expression of mitochondrial MnSOD. Loss of SIRT3 leads to increased mitochondrial ROS, which then enhances cellular transformation and tumor growth.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337010

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337010