• Title of article

    The Role of TET2 in Hematologic Neoplasms

  • Author/Authors

    Holmfeldt، نويسنده , , Linda and Mullighan، نويسنده , , Charles G.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2011
  • Pages
    2
  • From page
    1
  • To page
    2
  • Abstract
    TET2 encodes an enzyme that hydroxylates methylcytosine and is frequently targeted by loss-of-function mutations in myelodysplasia, myeloproliferative disorders, and acute myeloid leukemia. In this issue of Cancer Cell, two studies show that inactivation of Tet2 enhances hematopoietic stem cell self renewal and promotes the development of myeloproliferative disorders.
  • Journal title
    Cancer Cell
  • Serial Year
    2011
  • Journal title
    Cancer Cell
  • Record number

    1337542

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1337542