Title of article
Short Hairpin RNA Screen Reveals Bromodomain Proteins as Novel Targets in Acute Myeloid Leukemia
Author/Authors
Blobel، نويسنده , , Gerd A. and Kalota، نويسنده , , Anna and Sanchez، نويسنده , , Patricia V. and Carroll، نويسنده , , Martin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
2
From page
287
To page
288
Abstract
Targeting chromatin regulators for the treatment of malignancies has shown great promise, but also revealed significant challenges. By employing an elegant shRNA screen and a selective pharmacological inhibitor, a recent study published in Nature establishes the bromodomain protein Brd4 as novel target in acute myeloid leukemia (AML).
Journal title
Cancer Cell
Serial Year
2011
Journal title
Cancer Cell
Record number
1337612
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