• Title of article

    Silencing the Killers: Paracrine Immune Suppression in Pancreatic Cancer

  • Author/Authors

    Cox، نويسنده , , Adrienne D. and Olive، نويسنده , , Kenneth P.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2012
  • Pages
    2
  • From page
    715
  • To page
    716
  • Abstract
    Pancreatic cancers are characterized by high levels of inflammatory cells and profound immune suppression. In this issue of Cancer Cell, Bayne et al. and Pylayeva-Gupta et al. show that KRAS-driven, tumor cell-secreted GM-CSF recruits myeloid-derived suppressor cells to the stroma to abrogate tumor cell immune clearance by killer T lymphocytes.
  • Journal title
    Cancer Cell
  • Serial Year
    2012
  • Journal title
    Cancer Cell
  • Record number

    1337908