Title of article
Silencing the Killers: Paracrine Immune Suppression in Pancreatic Cancer
Author/Authors
Cox، نويسنده , , Adrienne D. and Olive، نويسنده , , Kenneth P.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
2
From page
715
To page
716
Abstract
Pancreatic cancers are characterized by high levels of inflammatory cells and profound immune suppression. In this issue of Cancer Cell, Bayne et al. and Pylayeva-Gupta et al. show that KRAS-driven, tumor cell-secreted GM-CSF recruits myeloid-derived suppressor cells to the stroma to abrogate tumor cell immune clearance by killer T lymphocytes.
Journal title
Cancer Cell
Serial Year
2012
Journal title
Cancer Cell
Record number
1337908
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