Title of article
A Big Step for SIRT7, One Giant Leap for Sirtuins… in Cancer
Author/Authors
Martيnez-Redondo، نويسنده , , Paloma and Santos-Barriopedro، نويسنده , , Irene and Vaquero، نويسنده , , Alejandro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
3
From page
719
To page
721
Abstract
Recently reporting in Nature, Barber et al. demonstrated that SIRT7 maintains critical features that define cancer cells by removing the acetylation mark on lysine 18 of histone H3. Interestingly, hypoacetylation of H3K18 has been described as a general marker of tumor prognosis and oncoviral transformation.
Journal title
Cancer Cell
Serial Year
2012
Journal title
Cancer Cell
Record number
1337911
Link To Document