A Case of Epithelial Myoepithelial Carcinoma - Correlation of IHC & Histopathological Findings

Epithelial myoepithelial carcinoma is a rare biphasic low grade neoplasm of salivary glands; it most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here a case of 58-year-old female presented with left cheek swelling of one-year duration. CT scan revealed a localized submandibular salivary gland tumor mass not involving surrounding tissues. Histological examination showed a mixture of ductal elements; cuboidal cells bordering small lumina surrounded by polygonal clear cells of myoepithelial component without any evidence of nuclear atypia or mitotic figures. Final diagnosis of epithelial myoepithelial carcinoma was made on the basis of characteristic morphological and immunohistochemical features.