Title of article
Dibutyltin perfluoroalkanecarboxylates: synthesis, NMR characterization and in vitro antitumour activity
Author/Authors
Martine Kemmer، نويسنده , , Hassan Dalil، نويسنده , , Monique Biesemans، نويسنده , , José C Martins، نويسنده , , Bernard Mahieu، نويسنده , , Ernst Horn، نويسنده , , Dick de Vos، نويسنده , , Edward R.T. Tiekink، نويسنده , , Rudolph Willem، نويسنده , , Marcel Gielen، نويسنده ,
Issue Information
دوفصلنامه با شماره پیاپی سال 2000
Pages
8
From page
63
To page
70
Abstract
Three dibutyltin perfluoroalkanecarboxylates have been synthesized, characterized by 1H-, 13C-, 19F- and 117Sn-NMR, Mössbauer, IR and mass spectroscopy. The structure of tetra-n-butylbis(trifluoroacetato)distannoxane has been elucidated by X-ray crystallography. The in vitro antitumour activity of the three compounds against seven human tumour cell lines was found to be as high as or even higher than that for reference compounds used clinically.
Keywords
Dibutyltin perfluoroalkanecarboxylates , NMR , Antitumour activity
Journal title
Journal of Organometallic Chemistry
Serial Year
2000
Journal title
Journal of Organometallic Chemistry
Record number
1370962
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