End-capped carbosiloxane dendrimers with cholesterol and pyridine derivatives

Dendritic carbosilanes containing 48 and 96 cholesterol as well as pyridine derivatives on the periphery have been prepared. Low generations in the inner shell were prepared by the use of iterative hydrosilation with dichloromethyl silane and alcoholysis with allyl alcohol. The cholesterol and pyridine derivatives containing dendrimers were prepared by the reaction of the SiCl group on parent dendrimers (G4-48Cl and G5-96Cl) and HOR (HOR=cholesterol, p-pyridinepropanol, and p-pyridinealdoxime) in the presence of TMEDA.