Hydrogen-bonding-directed molecular assembly of ferrocene bearing dipeptide chains (-l-Ala-l-Pro-NHPyMe) as an organometallic crystal architecture

The ferrocene 1 bearing the dipeptide chains, -l-Ala-l-Pro-NHPyMe, which was characterized by two intramolecular interchain hydrogen bondings between CO (Ala) and NH (another Ala) of each dipeptide chain to induce the chirality organized structure, was demonstrated to form a 1:2 complex with (1R,3S)-camphoric acid (CA). The single-crystal X-ray structure determination revealed a polymeric cocrystal composed of alternating units of 1 and two CA, which are linked by a network of hydrogen bonds to create the double-helical-like hydrogen-bonded molecular arrangement.