Title of article
Incorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation
Author/Authors
A. Pordea، نويسنده , , D. Mathis، نويسنده , , T.R. Ward، نويسنده ,
Issue Information
دوفصلنامه با شماره پیاپی سال 2009
Pages
7
From page
930
To page
936
Abstract
Incorporation of achiral biotinylated manganese-salen complexes into streptavidin yields artificial metalloenzymes for aqueous sulfoxidation using hydrogen peroxide. Four biotinylated salen ligands were synthesized and their manganese complexes were tested in combination with several streptavidin mutants, yielding moderate conversions (up to 56%) and low enantioselectivities (maximum of 13% ee) for the sulfoxidation of thioanisole.
Keywords
Biotin–avidin technology , Oxidation , Schiff base , enantioselective catalysis , Artificial metalloenzyme
Journal title
Journal of Organometallic Chemistry
Serial Year
2009
Journal title
Journal of Organometallic Chemistry
Record number
1375759
Link To Document