• Title of article

    Abnormal Immunoglobulin Levels in Iranian Patients with Hematologic Malignancies

  • Author/Authors

    Mashhadi، M.A. نويسنده , , Khazaei، HA نويسنده Associate Professor, Department of Immunology, Zahedan University of Medical Sciences, Zahedan, Iran , , Narouie، B نويسنده Researcher, Clinical Research Development Center, Zahedan University of Medical Sciences, Zahedan, Iran , , Niazi، AA نويسنده Assistant Professor, Department of Pathology, Zahedan University of Medical Sciences, Zahedan, Iran , , Moazzami، K نويسنده Immunology, Asthma and Allergy Research Institute, University of Tehran, Tehran, Iran , , Khademi، R نويسنده Registered Nurse, Zahedan University of Medical Sciences, Zahedan, Iran , , Hejazinia، F نويسنده Registered Nurse, Zahedan University of Medical Sciences, Zahedan, Iran , , Rezaei، N نويسنده Immunology, Asthma and Allergy Research Institute, University of Tehran, Tehran, Iran , , Ghasemi-rad، Mohammad نويسنده Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran ,

  • Issue Information
    فصلنامه با شماره پیاپی 39 سال 2009
  • Pages
    6
  • From page
    1
  • To page
    6
  • Abstract
    Introduction: Hematologic malignancies can be associated with dysregulation of the immune system. There are some conflicting data regarding serum immunoglobulin levels in patients with such malignancies. Material and method: In order to evaluate the humoral immunity of the patients with hematologic malignancies, 58 patients were enrolled in this study. 24 with acute lymphoblastic leukemia (ALL), 17 with acute myeloid leukemia (AML), eight with lymphoma, five with chronic lymphocytic leukemia, and four with multiple myeloma. Results: There were six cases with decreased serum IgG level (5 AML and 1 ALL). Forty patients with elevated serum IgG levels (69%).24 with elevated IgA and/or IgM level; 12 patients with elevation in all classes of immunoglobulin (8 ALL, 2 AML, and 2 lymphoma). Conclusion: Serum immunoglobulin levels can be abnormal in the patients with hematologic malignancies. Abnormalities of IgG, especially elevated level, seem to be the most frequent finding encountered in these patients.
  • Journal title
    Shiraz Electronic Medical Journal
  • Serial Year
    2009
  • Journal title
    Shiraz Electronic Medical Journal
  • Record number

    1416486

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1416486