Burden of maternal bipolar disorder on at-risk offspring: A controlled study on family planning and maternal care

Introduction r disorder (BD) is a highly incapacitating disease typically associated with high rates of familial dysfunction. Despite recent literature suggesting that maternal care is an important environmental factor in the development of behavioral disorders, it is unclear how much maternal care is dysfunctional in BD subjects. ive jective of this study was to characterize maternal care in DSM-IV/SCID diagnosed BD type I subjects compared to healthy controls with (PD) and without (NPD) other psychiatric diagnoses. als and methods -four BD mothers and 106 controls underwent an interview about family planning and maternal care, obstetrical complications, and mother–child interactions. K-SADS-PL questions about violence exposure were used to ascertain domestic violence and physical/sexual abuse. s hers were less likely to have stable unions (45.5%; p<0.01) or to live with the biological father of their children (33.3%; p<0.01), but had higher educational level and higher rates of social security use/retirement. They also had fewer children and used less contraceptive methods than controls. Children of BD women had higher rates of neonatal anoxia, and reported more physical abuse (16.1%; p=0.02) than offspring of NPD mothers. Due to BD mothersʹ symptoms, 33.3% of offspring suffered physical and/or psychological abuse. tions oc analysis, and the use of questions as a surrogate of symptoms as opposed to validated instruments. sion s one of few reports confirming that maternal care given by BD women is dysfunctional. BD psychopathology can lead to poor maternal care and both should be considered important environmental risk factors in BD, suggesting that BD psychoeducation should include maternal care orientation.