Enantioselective, potentiometric membrane electrodes based on cyclodextrins for the determination of l-histidine

Four enantioselective, potentiometric membrane electrodes based on carbon paste impregnated with α-, β-, 2-hydroxyl-3-trimethylammoniopropyl-β-(as chloride salt) and γ-cyclodextrins (γ-CDs) are proposed for the assay of l-histidine (l-his). The proposed electrodes showed near-Nernstian response over l-his but not over d-histidine (d-his). The recovery of l-his in the presence of d-his was higher than 99.10% with R.S.D. lower than 0.1%. The surfaces of the electrodes are easily renewable by simply polishing on an alumina paper.