Differential pulse voltammetric determination of ciprofibrate in pharmaceutical formulations using a glassy carbon electrode modified with functionalized carbon nanotubes within a poly(allylamine hydrochloride) film

A glassy carbon electrode (GCE) modified with functionalized multiwalled carbon nanotubes within a poly(allylamine hydrochloride) film (CNTs–PAH) to determine ciprofibrate using differential pulse voltammetry (DPV) is proposed. The CNTs/PAH film was previously valued and characterized with the zeta potential technique and scanning electronic microscopy (SEM). The DP voltammograms presented a ciprofibrate oxidation peak potential at 0.98 V in a 0.1 mol L−1 phosphate buffer solution (pH 7.0). The analytical curve was linear in the ciprofibrate concentration range from 1.33 × 10−5 to 1.32 × 10−4 mol L−1, with a detection limit of 8.34 × 10−6 mol L−1. Precise and accurate results are in agreement with those obtained by the chromatographic method at a 95% confidence level.