Title of article
Effect of dendrimers on pure acetylcholinesterase activity and structure
Author/Authors
Dzmitry Shcharbin، نويسنده , , D. and Jokiel، نويسنده , , M. and Klajnert، نويسنده , , B. and Bryszewska، نويسنده , , M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
56
To page
59
Abstract
The effect of polyamidoamine (PAMAM) dendrimers on activity and fluorescence of pure acetylcholinesterase (EC 3.1.1.7.) was studied. It has been shown that all dendrimers studied decreased the enzymatic activity of acetylcholinesterase. This effect depended on the type of dendrimers. The data on the intrinsic fluorescence have shown that the dendrimers changed acetylcholinesterase conformation and the strongest effect was induced by PAMAM G3.5 dendrimer.
Keywords
PAMAM dendrimer , fluorescence , Acetylcholinesterase , Conformation , Enzyme activity
Journal title
Bioelectrochemistry
Serial Year
2006
Journal title
Bioelectrochemistry
Record number
1451454
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