Title of article
Determination of 6-hydroxychlorzoxazone and chlorzoxazone in porcine microsome samples
Author/Authors
Cox، نويسنده , , Sherry K. and Hamner، نويسنده , , Tina and Bartges، نويسنده , , Joe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
6
From page
111
To page
116
Abstract
A simple, accurate and sensitive HPLC method for the in vitro determination of 6-hydroxychlorzoxazone and chlorzoxazone in porcine microsome samples is described. Chromatography was performed on a YMC-Pack ODS-AQ column using a mobile phase of 0.05% phosphoric acid pH 3–methanol (60:40, v/v). UV detection was carried out at 287 nm. The detector response was linear over the concentration range 25–2000 ng/ml. This assay produced quick, accurate, and repeatable results.
Keywords
Chlorzoxazone , Hydroxychlorzoxazone
Journal title
Journal of Chromatography B
Serial Year
2003
Journal title
Journal of Chromatography B
Record number
1454734
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