Title of article
Quantitative determination of astilbin in rabbit plasma by liquid chromatography
Author/Authors
Guo، نويسنده , , Jianming and Xu، نويسنده , , Qiang and Chen، نويسنده , , Ting، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
357
To page
360
Abstract
A simple method for determining the concentration of astilbin, a flavanone, in rabbit plasma has been developed. After liquid–liquid extraction, the flavanone was detected by HPLC on a 4.6-μm octadecylsilica column (Nova-Pak C-18) at 291 nm. Linear calibration graphs for astilbin were constructed from 0.44 to 22.17 μM. The limit of quantitation was 0.44 μM in plasma. The method has been applied to pharmacokinetic studies after a single i.v. and an oral administration of the compound to rabbits.
Keywords
Astilbin
Journal title
Journal of Chromatography B
Serial Year
2004
Journal title
Journal of Chromatography B
Record number
1456760
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