pH-Gradient spectrophotometric data files from flow-injection and continuous flow systems for two- and three-way data analysis

This paper describes a contribution to Chemometrics and Intelligent Laboratory Systems Elsevierʹs data base of files. Mixtures of nucleosides and a pharmaceutical preparation composed of cytosine and inosine-5′-monophosphate are analyzed using three different pH-gradient spectrophotometric flow-injection and continuous flow systems. Results for one of the flow-injection systems and for the continuous-flow system are reported for the first time in this paper. Resolution and quantitation of the constituents in the mixtures are given using a multivariate curve resolution method based on a constrained alternating least squares optimization.