On-line coupled liquid chromatography–gas chromatography

On-line coupled liquid chromatography–gas chromatography (LC–GC) is a powerful technique that combines the best features of LC and GC and is ideal for the analysis of complex samples. This review describes the unique features of on-line coupled LC–GC. The different interfaces and evaporation techniques are presented, along with their advantages and disadvantages. Guidelines are given for selecting a suitable LC–GC technique and representative applications are noted.