Title of article
High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts
Author/Authors
Cech، نويسنده , , Nadja B. and Eleazer، نويسنده , , Maqueita S. and Shoffner، نويسنده , , Lawresa T. and Crosswhite، نويسنده , , Mark R. and Davis، نويسنده , , Amanda C. and Mortenson، نويسنده , , Ashley M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
10
From page
219
To page
228
Abstract
Extracts of the plant Echinacea purpurea are widely used for medicinal purposes. Effective quality control of these extracts requires rapid methods to determine their chemical composition. A new method for analysis of caffeic acid derivatives and alkamides from Echinacea extracts has been developed. With this method, isomeric isobutylamides and 2-methylbutylamides can be distinguished, a capability that previously published methods have lacked. Quantitative analyses carried out with this method on E. purpurea extracts that have been stored for 18 months indicate that they contain caftaric acid, cichoric acid, and undeca-2Z,4E-diene-8,10-diynoic acid isobutylamide at concentrations of 0.7, 0.71 and 2.0 mg/mL, respectively.
Keywords
phenolics , Alkamides , Alkylamides , Isobutylamides , Caffeic acid derivatives , Caftaric acid , Dodeca-2E , 8Z , HPLC , 10Z-tetraenoic acid , 4E , Electrospray ionization mass spectrometry , ESI-MS , Quadrupole ion trap , Echinacea purpurea , Cichoric acid
Journal title
Journal of Chromatography A
Serial Year
2006
Journal title
Journal of Chromatography A
Record number
1524656
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